Status:
NOT_YET_RECRUITING
Revisiting the Concept of Nerve Sparing Radical Hysterectomy
Lead Sponsor:
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Conditions:
Cervical Cancers
Eligibility:
FEMALE
18+ years
Brief Summary
Nerve-sparing radical hysterectomy aims to preserve the autonomic innervation of pelvic organs. In most studies, the preservation of the parasympathetic component of pelvic innervation is achieved by ...
Detailed Description
The concept of preserving pelvic autonomic innervation during radical hysterectomy was first introduced by Yabuki, who emphasized the relevance of pelvic neuroanatomy in supporting nerve-sparing techn...
Eligibility Criteria
Inclusion
- (i) age ≥18 years; (ii) histologically confirmed cervical cancer; (iii) indication for type C1 (nerve-sparing) radical hysterectomy according to ESGO guidelines; and (iv) a minimum of 90 days of postoperative follow-up.
Exclusion
- (i) withdrawal of consent; (ii) prior abdominal and/or pelvic surgery; (iii) pre-existing urinary incontinence, detrusor overactivity, or detrusor underactivity; and (iv) pre-existing anorectal dysfunction Staging and architectural grade were defined according to the 2018 International Federation of Gynecology and Obstetrics (FIGO) recommendations, and histological subtypes were classified based on the World Health Organization (WHO) criteria
Key Trial Info
Start Date :
June 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
May 1 2027
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT06999824
Start Date
June 1 2025
End Date
May 1 2027
Last Update
May 31 2025
Active Locations (1)
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1
Fondazione IRCCS Istituto Nazionale dei Tumori di Milano
Milan, Lombardy, Italy, 20148