Status:

RECRUITING

A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event

Lead Sponsor:

AstraZeneca

Conditions:

Cardiovascular Disease

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

The purpose of this phase 3, randomized, placebo controlled, event-driven study is to assess the effect of AZD0780, an oral PCSK9 inhibitor, compared with placebo in reducing the risk of MACE-PLUS in ...

Eligibility Criteria

No eligibility criteria provided.

Key Trial Info

Start Date :

June 4 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 26 2029

Estimated Enrollment :

15100 Patients enrolled

Trial Details

Trial ID

NCT07000357

Start Date

June 4 2025

End Date

October 26 2029

Last Update

February 27 2026

Active Locations (1227)

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Page 1 of 307 (1227 locations)

1

Research Site

Birmingham, Alabama, United States, 35205

2

Research Site

Fairhope, Alabama, United States, 36532

3

Research Site

Foley, Alabama, United States, 36535

4

Research Site

Huntsville, Alabama, United States, 35801

A Phase III Study of AZD0780 on Major Adverse CV Events in Patients With a History of ASCVD Events or at High Risk for a First Event | DecenTrialz