Status:

RECRUITING

Dobutamine During Major Abdominal Surgery

Lead Sponsor:

University of Hamburg-Eppendorf

Conditions:

Intraoperative Myocardial Depression

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The PUSH-1 trial is a randomized, single-center pilot trial investigating whether dobutamine administration is feasible in patients having major abdominal surgery.

Eligibility Criteria

Inclusion

  • Consenting patients ≥18 years scheduled for elective major abdominal surgery under general anesthesia (expected surgery duration ≥ 120 minutes)
  • Planned continuous intraarterial blood pressure monitoring using an arterial catheter for clinical indications not related to the trial

Exclusion

  • Emergency surgery
  • Liver or kidney transplantation surgery
  • Status of post transplantation of kidney, liver, heart, or lung
  • Pregnancy
  • Heart rhythms other than sinus rhythm

Key Trial Info

Start Date :

June 16 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 1 2026

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT07000994

Start Date

June 16 2025

End Date

April 1 2026

Last Update

June 17 2025

Active Locations (1)

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1

University Medical Center Hamburg-Eppendorf

Hamburg, Hamburg, Germany, 20246