Status:

RECRUITING

Ischemic Preconditioning in Osteoarthritis and Back Pain

Lead Sponsor:

University of Illinois at Chicago

Collaborating Sponsors:

National Institute on Disability, Independent Living, and Rehabilitation Research

Conditions:

Low Back Pain

Knee Osteoarthritis

Eligibility:

All Genders

50+ years

Phase:

NA

Brief Summary

We are examining the use of restricted blood flow, through full occlusion, on a single thigh for 50 minutes (5 minutes on, 5 minutes off), completed every other day for 2 weeks to improve function in ...

Eligibility Criteria

Inclusion

  • Reported Knee Pain using ACR Criteria
  • Reported Back Pain using ODI Criteria \> 12
  • Ability to walk for at least 3 minutes without the use of aids
  • Ability to provide written informed consent

Exclusion

  • Younger than 50 years old
  • History of Knee or Hip Replacements
  • History of steroid injection within the previous 6 months
  • Presence of neuromuscular joint condition that affects lower extremity function
  • History of blood clots in the leg or any condition in which compression of the thigh is contraindicated
  • History of heart failure or thrombosis
  • Allergic to ultrasound gel
  • History of spine surgery
  • Non-English speaker
  • Currently pregnant or intends to become pregnant during the study

Key Trial Info

Start Date :

September 12 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2026

Estimated Enrollment :

24 Patients enrolled

Trial Details

Trial ID

NCT07003113

Start Date

September 12 2025

End Date

December 31 2026

Last Update

November 17 2025

Active Locations (1)

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Human and Sport Performance Lab

Chicago, Illinois, United States, 60608