Status:

RECRUITING

A Study Comparing Tarlatamab, Durvalumab, Carboplatin, and Etoposide Versus Durvalumab, Carboplatin, and Etoposide in First-line Extensive Stage Small-Cell Lung Cancer (ES-SCLC)

Lead Sponsor:

Amgen

Collaborating Sponsors:

AstraZeneca

Conditions:

Small-cell Lung Cancer

Extensive Stage Small-cell Lung Cancer

Eligibility:

All Genders

18-99 years

Phase:

PHASE3

Brief Summary

The main objective of the study is to compare the efficacy of tarlatamab in combination with durvalumab, carboplatin and etoposide to the combination of durvalumab, carboplatin and etoposide on prolon...

Eligibility Criteria

No eligibility criteria provided.

Key Trial Info

Start Date :

August 18 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 15 2029

Estimated Enrollment :

330 Patients enrolled

Trial Details

Trial ID

NCT07005128

Start Date

August 18 2025

End Date

July 15 2029

Last Update

February 27 2026

Active Locations (131)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 33 (131 locations)

1

Saint Bernards Medical Center

Jonesboro, Arkansas, United States, 72401

2

University of California Los Angeles

Santa Monica, California, United States, 90404

3

Presbyterian Intercommunity Hospital Health Whitter Hospital

Whittier, California, United States, 90602

4

Yale New Haven Hospital

New Haven, Connecticut, United States, 06510

A Study Comparing Tarlatamab, Durvalumab, Carboplatin, and Etoposide Versus Durvalumab, Carboplatin, and Etoposide in First-line Extensive Stage Small-Cell Lung Cancer (ES-SCLC) | DecenTrialz