Inclusion Criteria:

• Participant not afflicted by the disease under investigation and without ophthalmological pathology
• Person matched in age (+/- 5 years) and gender to a case (patient with PXE in pre-atrophic stages included in the PXE cohort)
• Signature of informed consent for participation in the protocol
• Adult at time of inclusion Criteria for non-inclusion of research subjects
• Known ophthalmological diseases (maculopathy, glaucoma, optic neuropathy, retinopathy whatever the aetiology)
• Known severe myopia, defined by a sphere > - 6 dioptres
• Diabetic subject
• Unable to carry out the ophthalmological examinations of the study
• Pregnant, breast-feeding or parturient woman
• Person undergoing psychiatric care under constraint
• Person subject to a legal protection measure
• Person not affiliated or not benefiting from a social security scheme

Exclusion Criteria:

• Ophthalmic pathology (maculopathy, glaucoma, optic neuropathy, retinopathy, whatever the etiology) discovered during the ophthalmic workup
• AngioOCT examination inexploitable (artifact and/or image quality less than 50/100 even after pupillary dilation)
• Severe myopia (sphere > - 6 dioptres) discovered during the ophthalmic workup.

Case inclusion critera :

• Patient diagnosed with pseudoxanthoma elasticum, defined according to Plomp's criteria: two out of three features related to PXE: (1) two pathogenic mutations in the ABCC6 gene, and/or (2) disease-specific dermatological changes and/or (3) disease-specific ocular changes;
• Included in the PXE cohort ;
• With pre-atrophic damage, i.e. at least one eye without choroidal neovessels on OCT-A, without previous intravitreal injection of anti-VEGF, and without major retinal atrophy (less than 2 papillary diameters);
• who have had an angiographic OCT (performed during follow-up consultations) with usable results (no artifacts and image quality of 50/100 or better) ;
• patient's non-objection to participation in a study

Case criteria for non-inclusion :

• Other known ophthalmological pathology (maculopathy, glaucoma, optic neuropathy, retinopathy of any etiology)
• Severe myopia, defined by a sphere > - 6 dioptres
• Diabetic subject