Status:

RECRUITING

A Study of Treatment-Related Toxicities and Quality of Life After Local Therapy in Chinese Breast Cancer Patients

Lead Sponsor:

FangYi

Conditions:

Breast Neoplasms

Quality of Life (QOL)

Eligibility:

FEMALE

18+ years

Brief Summary

This study, called PERSEVERE, examines how local treatment for early breast cancer affects people's health and daily lives over time. People who join the study will have early-stage breast cancer and...

Detailed Description

PERSEVERE is a prospective, multi-modal cohort study designed to evaluate treatment-related toxicities and quality of life in people with stage I-III early breast cancer receiving local therapy in Chi...

Eligibility Criteria

Inclusion Criteria:

  • Women aged 18 years or older
  • Diagnosed with stage I, II, or III invasive breast cancer confirmed by pathology or cytology
  • No signs of metastatic disease (cancer that has spread to other parts of the body)
  • Scheduled to receive local treatment, including:

Surgery

And/or neoadjuvant or adjuvant therapy such as chemotherapy, radiation, hormone therapy, or targeted therapy

  • Willing and able to complete health questionnaires and attend follow-up visits
  • Has given written informed consent to join the study

Exclusion Criteria:

  • Have metastatic breast cancer or local recurrence
  • Have already received curative treatment (surgery, chemo, etc.) for the current breast cancer before joining the study
  • Are currently pregnant or breastfeeding
  • Have a history of another cancer within the past 5 years (except for non-melanoma skin cancer or in-situ cervical cancer)
  • Are unable to participate in the study due to mental, physical, or legal reasons (for example, under legal guardianship or imprisonment)

Key Trial Info

Start Date :

April 7 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2028

Estimated Enrollment :

3000 Patients enrolled

Trial Details

Trial ID

NCT07010939

Start Date

April 7 2025

End Date

December 31 2028

Last Update

September 12 2025

Active Locations (3)

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Page 1 of 1 (3 locations)

1

National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

Beijing, Beijing Municipality, China, 100021

2

Cancer Hospital Chinese Academy of Medical Sciences, Shenzhen Center

Shenzhen, Guangdong, China, 518116

3

Shanxi Cancer Hospital

Taiyuan, Shanxi, China, 030013