Active, Not Recruiting
COBRA: Cancer, Older Adults, Balance and Resistance Activities
Led by Memorial Sloan Kettering Cancer Center · Updated on 2026-04-24
38
Participants Needed
6
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to find out whether an 8-week digital health promotion program called COBRA is a safe and practical (feasible) option for older adults with cancer/OAC.
CONDITIONS
Official Title
COBRA: Cancer, Older Adults, Balance and Resistance Activities
Who Can Participate
Eligibility Criteria
You may qualify if you...
Older Adult Patients with Cancer
- Are within 1 year of completion of primary therapy for cancer OR have a diagnosis of metastatic cancer;
- For the purpose of this study, primary therapy is defined as treatment of curative intent, first-line or later, from which the individual is advancing to active surveillance or follow-up with or without maintenance therapy.
- Individuals with metastatic cancer may be included provided they have stable disease or better per most recent restaging exam at time of enrollment.
i. Patients with stable metastatic bony disease at most recent restaging exam and a score of 0-2 on the Functional Pain Scale (FPS69; Appendix 18) are eligible. The PI will consult with the Rehab Med co-PI for FPS scores of 3 or greater, by patient request or PI discretion.
ii. Patients with symptomatic visceral metastases will be evaluated on a case-by-case basis at time of enrollment.
- Are aged 65 years and older, with no upper age limit;
- ECOG PS 0-3 or Karnofsky PS greater than or equal to 40;
- Can read and speak English;
- Self-report access to internet connection sufficient to support videoconferencing.
Clinicians
- Licensed clinician (MD, RN, APP) with an interest in the care of older adults with cancer.
You will not qualify if you...
Older Adult Patients with Cancer
- Have any cognitive impairment, neurologic, musculoskeletal, or other comorbid condition (as assessed by their provider) that would prevent the individual from engaging with the digital health coaching program or complete study assessments or engage in progressive intensity levels of physical activity
- Have a neurologic, musculoskeletal, or other comorbid condition that would impede their ability to safely engage in progressive intensity levels of physical activity (as assessed by their provider). Patients with metastatic disease and suspected interim progression since last restaging exam will be referred back to their primary oncology care team for evaluation prior to enrollment.
- Have activity restrictions post-surgery at the time of enrollment
Clinicians No expected exclusions
Trial Site Locations
Total: 6 locations
1
Memorial Sloan Kettering Monmouth (Consent only)
Middletown, New Jersey, United States, 07748
Status Unknown
2
Memorial Sloan Kettering Bergen (Consent Only)
Montvale, New Jersey, United States, 07645
Status Unknown
3
Memorial Sloan Kettering Suffolk-Commack (Consent Only)
Commack, New York, United States, 11725
Status Unknown
4
Memorial Sloan Kettering Westchester (Consent only)
Harrison, New York, United States, 10604
Status Unknown
5
Memorial Sloan Kettering Cancer Center (All Protocol Activites)
New York, New York, United States, 10065
Status Unknown
6
Memorial Sloan Kettering Nassau (Consent Only)
Uniondale, New York, United States, 11553
Status Unknown
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
1
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