Status:
RECRUITING
Acoustics as a Metric of Airway Pressure in Premature Infants Using Bubble Continuous Positive Airway Pressure
Lead Sponsor:
McGill University Health Centre/Research Institute of the McGill University Health Centre
Collaborating Sponsors:
Northwestern University
Conditions:
Preterm Infant
Eligibility:
All Genders
28-32 years
Brief Summary
This is an observational, proof-of-concept, feasibility study where 30 preterm infants on bubble CPAP with gestational age \< 32+0 weeks will be recruited from the neonatal intensive care unit (NICU) ...
Detailed Description
Continuous positive airway pressure (CPAP) is an essential, non-invasive therapy for treating various respiratory conditions in the Neonatal Intensive Care Units (NICU). CPAP is an effective treatment...
Eligibility Criteria
Inclusion Criteria:
- Infants on bCPAP with gestational age < 32+0 weeks
- Postmenstrual age between 28+0 and 36+6 weeks at the time of the study
- Postnatal age greater than 168 hours (7 days) at the time of the study
- On the bubble CPAP device with binasal prongs at the time of the study
- Receiving bubble CPAP levels of 5 to 7 cm H2O with gas flows between 6L/min and 10L/min at the time of the study
Exclusion Criteria:
- Infants with known major congenital anomalies
- Infants with known congenital heart disorders
- Infants with known neuromuscular disease
- Infants receiving ventilator-derived CPAP at the time of the study
- Infants receiving CPAP via a nasal mask interface at the time of the study
- Infants receiving inotropes, narcotics or sedative agents at the time of the study
- Infants deemed clinically unstable for the study by the attending neonatologist
Key Trial Info
Start Date :
April 3 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2026
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT07060833
Start Date
April 3 2025
End Date
December 1 2026
Last Update
March 30 2026
Active Locations (1)
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1
McGill University Health Center
Montreal, Quebec, Canada, H4A 3J1