Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
ID07091604

Objective Skin Pigmentation Assessment Using Non-invasive Imaging in Healthy Volunteers and Patients with Skin Disease An Observational Study

Led by Leiden University Medical Center · Updated on 2025-08-01

600

Participants Needed

1

Research Sites

78 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Accurate measurement of skin pigmentation is important in dermatology to diagnose and treat various skin conditions properly. Traditional methods like visual inspection or using the Fitzpatrick skin type can be subjective, biased, and often focus on lighter skin tones, which may lead to misdiagnosis or inappropriate care for people with darker skin. This research aims to find better, more objective ways to measure skin color using modern non-invasive imaging technologies. Researchers will use tools such as colorimetry and multispectral imaging to assess skin pigmentation more precisely. The study includes two groups: healthy adults and adults with skin diseases. They will measure the melanin index, which shows the amount of pigment in the skin, and compare these values across different body areas and various skin tones and conditions. Participants will be assessed for skin pigmentation using these advanced imaging techniques. The study will measure the melanin index at the start to understand variations in skin color. This information may help improve diagnosis and treatment of skin diseases for people of all skin types. The study requires participants to be at least 18 years old and able to understand Dutch or English.

CONDITIONS

Official Title

An Observational Study to Assess Objective Skin Pigmentation Variation.

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Ability to understand oral and written Dutch or English
Not Eligible

You will not qualify if you...

  • Extensive tattoos covering more than 50% of the total body area
  • Recent extensive sun exposure such as sun tanning booth or stay in a tropical country in the last 3 weeks
  • Use of self-tanner products in the last 3 weeks
  • For patients: extensive skin lesions covering more than 50% of the total body area

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Leiden University Medical Center

Leiden, Leiden, Netherlands, 2333 ZG

Actively Recruiting

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Research Team

D

Deepak M.W. Balak

L

Lotte J. van den Oord

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

Frequently Asked Questions

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