Status:

RECRUITING

18F-Pentixafor PET in Hematologic Malignancies

Lead Sponsor:

First Affiliated Hospital of Zhejiang University

Conditions:

Hematological Malignancies

Eligibility:

All Genders

18-80 years

Brief Summary

The aim of this study is to evaluate the efficacy of 18F-Pentixafor PET imaging in the diagnosis, staging and response evaluation of hematological malignancies.

Detailed Description

18F-FDG PET imaging based on the principle of glucose metabolism imaging is currently dominant in the staging and efficacy evaluation of lymphoma, but it is not suitable for a wider range of hematolog...

Eligibility Criteria

Inclusion Criteria:

  1. Age of 18-80 years old, both sexes, with behavioral capacity;
  2. patients with suspected or confirmed hematological malignancies;
  3. 18F-FDG PET or other imaging examinations should be performed according to the treatment plan;
  4. For suspected patients, biopsy or needle biopsy is expected to obtain pathological results;
  5. Can provide informed consent, can understand and comply with the requirements of the study.

Exclusion Criteria:

  1. pregnant and lactating women;
  2. patients with fear or radiophobia, or with mental disorder or primary affective disorder;
  3. received ionizing radiation outside the scope of this study for clinical medical or scientific research purposes within the past year, resulting in an annual radiation exposure dose exceeding 50 mSv;
  4. received investigational drugs or devices of uncertain efficacy or safety within 1 month;
  5. Any condition that the chairpersons of the study consider that any link related to the study may cause harm or have potential harm.

Key Trial Info

Start Date :

July 1 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2029

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT07122674

Start Date

July 1 2025

End Date

December 1 2029

Last Update

August 14 2025

Active Locations (1)

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1

The First Affiliated Hospital of Zhejiang University School of Medicine

Hangzhou, Zhejiang, China, 310003