Status:

NOT_YET_RECRUITING

An Evaluation of the Neuromuscular Junction in Neonates Using the TetraGraph

Lead Sponsor:

Joseph D. Tobias

Conditions:

Surgery

Eligibility:

All Genders

28-25 years

Phase:

NA

Brief Summary

The goal of this study is to use electromyography-based train-of-four monitoring (TetraGraph™ Neuromuscular Transmission Monitor) as a means of evaluating differences in neuromuscular transmission bet...

Eligibility Criteria

Inclusion

  • ASA 1-3 patients
  • Aged 28 days - 3 months or ≥ 12 years
  • Undergoing a surgical procedure with a volatile-agent based anesthetic that does not require administration of a neuromuscular blocking agent

Exclusion

  • Patients with history of a peripheral neurologic or neuropathic disorder
  • Patients in whom the upper extremity cannot be used for TOF monitoring
  • Patients undergoing a surgical procedure in which neuromuscular blockade is required
  • Edematous patients
  • Patients receiving total intravenous anesthesia (TIVA)

Key Trial Info

Start Date :

January 1 2026

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2027

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT07133412

Start Date

January 1 2026

End Date

December 1 2027

Last Update

October 27 2025

Active Locations (1)

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1

Nationwide Children's Hospital

Columbus, Ohio, United States, 43205