Status:
RECRUITING
High Flow Nasal Cannula Versus High Velocity Nasal Insufflation for Weaning
Lead Sponsor:
Assiut University
Conditions:
Weaning From Mechanical Ventilation
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
In intensive care units (ICUs), approximately 10% to 15%of patients ready to be separated from a ventilator experience extubation failure leading to reintubation. In patients considered at high risk, ...
Detailed Description
All patients were submitted to, History, Clinical examination, ABG, Laboratory assessment: as needed, ICU scores: APACHE II score. Weaning from mechanical ventilation procedure: The procedure of wea...
Eligibility Criteria
Inclusion
- Adults (≥18 years) intubated for \>24 hours due to acute respiratory failure, identified as high-risk for extubation failure AND fulfilling standard readiness-to-wean criteria (e.g., resolution of cause of intubation, adequate gas exchange \[P/F ≥150\], hemodynamic stability, spontaneous breathing trial \[SBT\] success)
Exclusion
- Patients with central nervous system disorders unrelated to hypercapnic encephalopathy or hypoxemia.
- Patients with post arrest encephalopathy.
- Patient with previous tracheotomy.
- Patients who received noninvasive ventilation without subsequent intubation.
- Patients with end organ failure.
Key Trial Info
Start Date :
February 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 1 2025
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT07133698
Start Date
February 1 2024
End Date
October 1 2025
Last Update
August 21 2025
Active Locations (1)
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1
Assiut University hospital
Asyut, Egypt, 71515