Status:
NOT_YET_RECRUITING
Mitochondrial Function in Peripheral Blood Mononuclear Cells, Muscle, and Skin of Long COVID Patients
Lead Sponsor:
Universitair Ziekenhuis Brussel
Conditions:
Long COVID
Post-COVID-19 Condition
Eligibility:
All Genders
18+ years
Brief Summary
Mitochondria are structures inside cells that are responsible for producing energy from nutrients through a series of steps, using oxygen. To have an idea of how well the mitochondria can produce ener...
Eligibility Criteria
Inclusion
- Individuals with long COVID:
- Inclusion criteria:
- Long COVID diagnosis, based on the WHO definition;
- Presence of long COVID symptoms for a minimum of 6 months.
- History of confirmed or documented SARS-CoV-2 infection.
- Adult (≥18 years of age).
- Post-COVID-19 Functional Status Scale grade 2-4, while they had a grade 0 before the SARS-CoV-2 infection.
- Exclusion criteria:
- Pre-existing chronic diseases potentially affecting the functional status scale.
- Treatment with metabolism altering drugs.
- \> 10 standard units of alcohol (10 grams of alcohol/glass) per week.
- Unable to understand oral and written instructions in Dutch, French or English.
- Allergies to medical adhesive bandages.
- Porphyria and other skin conditions aggravated by sunlight.
- Convalescent individuals
- Inclusion criteria:
- History of confirmed or documented SARS-CoV-2 infection.
- Complete recovery after the SARS-CoV-2 infection, no history of long COVID based on the WHO definition;
- Post-COVID-19 Functional Status Scale \[2\] grade 0 both before the infection and currently.
- Adult (≥18 years of age).
- Exclusion criteria:
- Pre-existing chronic non-communicable diseases (e.g. hypertension, chronic respiratory diseases, diabetes).
- Treatment with metabolism altering drugs.
- \> 10 standard units of alcohol (10 grams of alcohol/glass) per week.
- Unable to understand oral and written instructions in Dutch, French or English.
- Allergies to medical adhesive bandages.
- Porphyria and other skin conditions aggravated by sunlight.
Exclusion
Key Trial Info
Start Date :
October 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 1 2026
Estimated Enrollment :
54 Patients enrolled
Trial Details
Trial ID
NCT07134673
Start Date
October 1 2025
End Date
July 1 2026
Last Update
August 21 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Laarbeeklaan 101
Jette, Brussels Capital, Belgium, 1090