Status:
COMPLETED
Sepsis and Thiol-Disulfide Balance in Emergency Department
Lead Sponsor:
Sakarya University
Conditions:
Sepsis
Oxidative Stress
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The aim of this study was to determine the effectiveness of thiol-disulfide homeostasis in predicting diagnosis and mortality in sepsis patients, and to compare it with other inflammatory markers.
Detailed Description
Sepsis is a serious illness with high mortality rates triggered by infection-associated pathogenesis involving oxidative stress dysfunction. This study aims to elucidate the diagnostic efficacy of cha...
Eligibility Criteria
Inclusion
- Patients aged 18 and above who met the diagnostic criteria were included in the study
Exclusion
- Who did not meet the criteria for sepsis diagnosis according to the quick Sequential Organ Failure Assessment score
- Individuals with malignancy, acute coronary syndrome, acute cerebrovascular event, acute/chronic kidney/liver failure, rheumatologic diseases, febrile neutropenia, immunosuppressive disorders, corticosteroid use, and those
- Individuals with a history of antibiotic use within the last week
Key Trial Info
Start Date :
June 15 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 15 2018
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT07134868
Start Date
June 15 2018
End Date
December 15 2018
Last Update
August 21 2025
Active Locations (1)
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1
Sakarya University
Sakarya, Adapazarı, Turkey (Türkiye), 54050