Status:

ACTIVE_NOT_RECRUITING

In Vitro Study on Donor Corneas Preservation in IRESTORE Storage Medium. A Post Marketing Interventional Study on Device

Lead Sponsor:

Fondazione IRCCS Policlinico San Matteo di Pavia

Conditions:

Donor Corneas Preservation

Eligibility:

All Genders

Brief Summary

Donor corneas are harvested and then stored in the Eye Bank to maintain their viability until analysis and subsequent release for transplantation. The storage period of donor corneas is classified in ...

Detailed Description

The device used in the study is classified as class II A (medium risk) The device iRestore Conservation, sterile liquid for the preservation of corneal grafts in hypothermic conditions up to 14 days. ...

Eligibility Criteria

Inclusion

  • Inclusion criteria (donor):
  • Medical history of a disease that excludes donation;
  • serological positivity (HBV, HCV, HIV);
  • Inclusion criteria (cornea):
  • low endothelial cell density (\<2000 cells/mm2);
  • stromal opacities.
  • Exclusion criteria (cornea):
  • Severe endothelial dystrophy;
  • massive endothelial mortality;
  • marked stromal opacities.

Exclusion

    Key Trial Info

    Start Date :

    March 7 2025

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    November 7 2025

    Estimated Enrollment :

    15 Patients enrolled

    Trial Details

    Trial ID

    NCT07134946

    Start Date

    March 7 2025

    End Date

    November 7 2025

    Last Update

    August 21 2025

    Active Locations (1)

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    Page 1 of 1 (1 locations)

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    Fondazione IRCCS Policlinico San Matteo

    Pavia, Italy, 27100