Status:
NOT_YET_RECRUITING
Hemodynamic Evaluation and Assessment of DIRECT myocaRdial and Sublingual Capillary Perfusion in Thoracic Surgery Patients on Cardiopulmonary Bypass
Lead Sponsor:
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Conditions:
Microcirculatory Perfusion
Eligibility:
All Genders
Brief Summary
After cardiac surgery, some people may experience problems with their circulation or how well the heart pumps. This can occur because the smallest blood vessels in the heart do not function properly. ...
Detailed Description
Congruence of micro- and macrocirculation is essential in participants during the postcardiotomy period to maintain hemodynamic stability \[1,2\]. At the capillary (i.e. microcirculatory) level, gas a...
Eligibility Criteria
Inclusion
- Adult patients (18 years or older)
- Use of central cannulated CPB through median sternotomy
- Patients undergoing valve surgery or a supracoronary ascending aorta replacement
- Good LVEF and RVF
- LAVI \< 50 ml/m2, and right atrial volume index (RAVI) \< 45 ml/m2,
Exclusion
- Patients with significant coronary artery disease (i.e., CAD-RADS ≥ 4, and/or stenosis of ≥ 70% as observed in coronary angiogram) or previous infarctions, including ST-elevated myocardial ischemia (STEMI) or non-ST-elevated myocardial ischemia (N-STEMI)
- Patients with echocardiographically observed regional wall motion abnormalities, hypokinesis, or akinesis in the coronary territories
- Patients undergoing left atrial appendage amputation (LAAA)
- Patients with AF
- High-risk patients, as defined by a EuroSCORE II ≥ 8%
Key Trial Info
Start Date :
October 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 1 2026
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT07135700
Start Date
October 1 2025
End Date
October 1 2026
Last Update
August 22 2025
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