Status:
RECRUITING
Sleeve Lobectomy Following Neoadjuvant Therapy in NSCLC
Lead Sponsor:
Shanghai Chest Hospital
Collaborating Sponsors:
Sir Run Run Shaw Hospital
Second Affiliated Hospital, School of Medicine, Zhejiang University
Conditions:
Lung Cancer
Neoadjuvant Therapy
Eligibility:
All Genders
18+ years
Brief Summary
The goal of this observational, retrospective, multicenter cohort study is to evaluate the surgical and oncologic outcomes of sleeve lobectomy performed via minimally invasive (RATS/VATS) or open thor...
Eligibility Criteria
Inclusion
- Age ≥ 18 years
- Histologically confirmed NSCLC
- Undergoing sleeve lobectomy with curative intent
- Receipt of neoadjuvant therapy (chemotherapy, immunotherapy, target therapy, etc.)
- Surgical approach: either minimally invasive (VATS or RATS) or open thoracotomy
- Availability of complete perioperative and follow-up data (minimum 12-month follow-up or until death)
- Signed informative consent
Exclusion
- Sublobar resections (e.g., segmentectomy) or pneumonectomy
- Absence of neoadjuvant therapy
- Purely diagnostic surgical procedures
- Incomplete medical records or lost to follow-up
- Metastatic (stage IV) disease at time of surgery
Key Trial Info
Start Date :
September 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2026
Estimated Enrollment :
400 Patients enrolled
Trial Details
Trial ID
NCT07135856
Start Date
September 1 2025
End Date
December 1 2026
Last Update
December 31 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Shanghai Chest Hospital
Shanghai, Shanghai Municipality, China, 200000