Status:
COMPLETED
Risk Factors of Postoperative Acute Kidney Injury and Mortality Among Hospitalized Patients Undergoing Major Surgery
Lead Sponsor:
Peking University First Hospital
Conditions:
Acute Kidney Injury
Major Surgery Under General Anesthesia
Eligibility:
All Genders
18-99 years
Brief Summary
The goal of this retrospective observational study is to learn about the intervenable risk factors of postoperative acute kidney injury (AKI) and in-hospital mortality among adult patients undergoing ...
Detailed Description
Acute Kidney Injury (AKI), characterized by a rapid decline of kidney function, is a common but serious postoperative complication in surgical patients, with an incidence ranging from 5.3% to 18.4%. P...
Eligibility Criteria
Inclusion
- Age≥18 years
- Hospitalized at Peking University First Hospital (PKUFH) between January 1, 2018, and December 31, 2020
- Undergoing major surgery during hospital stay
Exclusion
- With fewer than two serum creatinine (SCr) measurements during hospitalization, or lack of postoperative SCr assessment
- With pre-exsiting CKD G5 (including long-term dialysis, prior/current kidney transplantation, or baseline estimated glomerular filtration rate \[eGFR\]\<15mL/min/1.73m\^2) at admission
- Undergoing radical or partial nephrectomy during current hospitalization
- Developing AKI prior to surgery or within 24 hours after admission (with admission diagnosis of AKI or meeting AKI criteria within 24 hours)
- With hospital stay \< 24 hours
Key Trial Info
Start Date :
January 1 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 31 2020
Estimated Enrollment :
21533 Patients enrolled
Trial Details
Trial ID
NCT07136194
Start Date
January 1 2018
End Date
December 31 2020
Last Update
August 22 2025
Active Locations (1)
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1
Peking University First Hospital
Beijing, Beijing Municipality, China, 100034