Status:

COMPLETED

Complications and Failure of Centrally Inserted Central Catheters in Cardiac Surgical Patients

Lead Sponsor:

Azienda Ospedaliero-Universitaria Careggi

Conditions:

CRBSI - Catheter Related Bloodstream Infection

Central Venous Catheter

Eligibility:

All Genders

18+ years

Brief Summary

Central venous catheters, or CVCs, are medical devices used to deliver medications and blood products directly into a patient's large veins. They are now an essential part of modern hospital care, but...

Detailed Description

Over recent decades, numerous studies have examined the long-term complications associated with centrally inserted central catheters (CICCs). Among these, catheter-related bloodstream infections (CRBS...

Eligibility Criteria

Inclusion

  • Patients aged \>18 years.
  • Signed informed consent for contactable patients and those who will be attending the treatment center for follow-up visits.
  • Patients undergoing elective or emergency cardiac surgery during the study period.
  • Cardiac anesthesiologist performing the procedure with \>2 years of experience in cardiac surgery and with \>100 ultrasound-guided CICC placement procedures per year.
  • Patient with a triple- or quad-lumen CICC placed in the right internal jugular vein.

Exclusion

  • Patients with active endocarditis.
  • Patients with preoperative sepsis.
  • Patients with infection confirmed by another source.
  • Patients under 18 years of age.
  • Patients who died within 7 days of surgery.
  • Patients with a CICC already in place at the time of surgery.
  • Cardiac anesthesiologist with less than 2 years of cardiac surgery experience and/or fewer than 100 procedures per year.
  • Patients with a CICC placed in the left IJV, subclavian veins, or femoral veins.

Key Trial Info

Start Date :

June 1 2022

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 10 2025

Estimated Enrollment :

480 Patients enrolled

Trial Details

Trial ID

NCT07138690

Start Date

June 1 2022

End Date

August 10 2025

Last Update

September 3 2025

Active Locations (1)

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1

Cardiac ICU - Department of Anesthesia and Intensive Care - Careggi University Hospital

Florence, Italy, Italy, 50134