Status:
RECRUITING
Research on the Application of 99mTc-TCR-FAPI SPECT Imaging in Rheumatoid Arthritis
Lead Sponsor:
Luo Yaping
Collaborating Sponsors:
Peking Union Medical College Hospital
Conditions:
Rheumatoid Arthritis (RA)
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
This study proposes to evaluate 99mTc-CTR-FAPI SPECT imaging as a cost-effective, low-radiation, and widely accessible alternative to 68Ga-FAPI PET/CT for assessing synovial lesions in RA patients, ai...
Detailed Description
This study will enroll 20 rheumatoid arthritis patients meeting the 2010 ACR/EULAR classification criteria with moderate-to-high disease activity, with all participants undergoing both 99mTc-CTR-FAPI ...
Eligibility Criteria
Inclusion
- Age: 18-75 years old;
- Meet the classification criteria for rheumatoid arthritis of the American College of Rheumatology/European Union for Rheumatology in 2010;
- The highest disease activity in clinical practice (CDAI or SDAI score
Exclusion
- Patients with other autoimmune diseases;
- Patients with concurrent tumors;
- Women who are pregnant or planning to become pregnant, women in the preconception period, pregnant and lactating women, and women with child-rearing plans during the study period; Subjects of childbearing age need to take effective contraceptive measures during the research process;
- Active infection
- Suffering from claustrophobia or other mental disorders, with poor compliance resulting in inability to cooperate with this researcher; (6) Situations where other researchers consider it inappropriate to participate in this clinical trial.
Key Trial Info
Start Date :
May 10 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
April 28 2028
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT07138729
Start Date
May 10 2025
End Date
April 28 2028
Last Update
August 24 2025
Active Locations (1)
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1
Peking Union Medical College Hospital
Beijing, Beijing Municipality, China, 100730