Status:

NOT_YET_RECRUITING

Impact of Gastric Mesentery With Lymph Node Metastasis on Prognosis in Gastric Cancer Patients

Lead Sponsor:

Jichao Qin

Collaborating Sponsors:

Zhejiang University

Conditions:

Gastric Carcinoma

Eligibility:

All Genders

18-85 years

Brief Summary

This study aims to validate the predictive value of lymph node-metastasis gastric mesenteric regions and their quantitative involvement for gastric cancer prognosis by systematically examining lymph n...

Detailed Description

Prior to 2010, the gastric cancer nodal staging systems primarily consisted of two approaches: the UICC/AJCC classification (by the International Union Against Cancer/American Joint Committee on Cance...

Eligibility Criteria

Inclusion

  • Aged older than 18 years and younger than 85 years
  • Primary gastric adenocarcinoma confirmed by preoperative pathology result
  • cT2-4aN0-3M0 at preoperative evaluation according to the American Joint 8 Committee on Cancer (AJCC) Cancer Staging Manual 8th Edition
  • Patients who received gastrectomy with D2 lymphadenectomy plus complete mesogastric excision
  • American Society of Anesthesiologists (ASA) class I, II, or III
  • Written informed consent

Exclusion

  • Negative preoperative biopsy
  • Too late tumour stage or metastasis (cT4b/M1)
  • BMI\>30 kg/m2
  • Total gastrectomy or proximal gastrectomy
  • previous neoadjuvant chemotherapy or radiotherapy
  • Previous upper abdominal surgery
  • Combined with other malignant diseases
  • Reject operation

Key Trial Info

Start Date :

August 30 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

August 30 2030

Estimated Enrollment :

400 Patients enrolled

Trial Details

Trial ID

NCT07139418

Start Date

August 30 2025

End Date

August 30 2030

Last Update

August 24 2025

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