Status:

RECRUITING

Spontaneous Correction of Sagittal Imbalance After Isolated Lumbar Decompression

Lead Sponsor:

N.N. Priorov National Medical Research Center of Traumatology and Orthopedics

Collaborating Sponsors:

Burdenko Neurosurgery Institute

Pirogov National Medical Surgical Center

Conditions:

LUMBAR STENOSIS

Sagittal Imbalance

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Sagittal spinal imbalance may be caused by orthopedic problems, compression of the neural structures of the spinal canal, and pain syndrome (functional imbalance). Sagittal imbalance in combination wi...

Eligibility Criteria

Inclusion

  • 1\. Age 45 and over;
  • 2\. Radicular leg pain and/or neurogenic claudication with/without back pain, caused by single- or multi-level degenerative lumbar stenosis with/without spodylolisthesis, confirmed by MRI;
  • 3\. Planned isolated decompression of the spinal canal without implantation of any devices;
  • 4\. Symptoms persisting for at least 3 months prior to surgery;
  • 5\. Given written Informed Consent;
  • 6\. Able and agree to fully comply with the clinical protocol and willing to adhere to follow-up schedule and requirements.
  • Non-
  • 1\. Prior any lumbar surgery;
  • 2\. Scoliosis of any non-degenerative etiology (due to vertebral fractures, idiopathic, etc.);
  • 3\. Degenerative scoliosis \> 20 degrees;
  • 4\. Any contraindication or inability to undergo baseline and/or follow up MRI or X-ray as required per protocol;
  • 5\. Any other condition or situation that the investigator believes may interfere with the safety of the subject or the intent and conduct of the study;

Exclusion

  • 1\. Performed intraoperative discotomy;
  • 2\. Performed intraoperative iatrogenic instability of the lumbar segment (facetectomy, foraminotomy, etc.)

Key Trial Info

Start Date :

October 6 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 6 2027

Estimated Enrollment :

165 Patients enrolled

Trial Details

Trial ID

NCT07139938

Start Date

October 6 2025

End Date

October 6 2027

Last Update

December 11 2025

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Pirogov National Medical Surgical Center

Moscow, Russia, 105203

2

Burdenko Neurosurgery Institute

Moscow, Russia, 125047

3

Priorov National Medical Research Center of Traumatology and Orthopedics

Moscow, Russia, 127299