Status:

NOT_YET_RECRUITING

Surgery of Dystonia

Lead Sponsor:

Sohag University

Conditions:

Dystonia Stereotactic Surgery

Eligibility:

All Genders

10-70 years

Phase:

NA

Brief Summary

The goal of this clinical trial is to evaluate the safety and clinical outcomes of stereotactic surgery (Deep Brain Stimulation or Radiofrequency Lesioning) in patients with dystonia. The main questi...

Detailed Description

Detailed Description Dystonia is a chronic movement disorder characterized by sustained or intermittent muscle contractions, resulting in abnormal postures, repetitive movements, and functional disab...

Eligibility Criteria

Inclusion

  • Diagnosed with dystonia with at least 1-year duration since symptom onset.
  • Inadequate relief of dystonia following treatment with standard pharmacotherapies (e.g., levodopa, clonazepam, trihexyphenidyl, or baclofen) or botulinum toxin injections.

Exclusion

  • Previous DBS surgery.
  • Underwent DBS combined with another surgical procedure for dystonia (e.g., lesioning or peripheral denervation).
  • Cognitive dysfunction or other neuropsychiatric disorders.
  • Progressive neurological conditions other than dystonia.
  • Coagulopathy or bleeding disorders.

Key Trial Info

Start Date :

September 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2027

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT07140302

Start Date

September 1 2025

End Date

September 1 2027

Last Update

August 24 2025

Active Locations (1)

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Sohag Faculity of Medicine

Sohag, Egypt