Status:
NOT_YET_RECRUITING
The Effects of a Probiotic Food Supplement in Hyperuricaemia
Lead Sponsor:
Örebro University, Sweden
Conditions:
Hyperuricemia With or Without Gout
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The overall aim of the project is to determine whether a daily intake of health-promoting bacteria, known as probiotics, with or without a dietary fiber, affects uric acid levels in individuals with e...
Eligibility Criteria
Inclusion
- Signed informed consent prior to any study-related procedures
- Age 18-80 years old
- BMI range 17.5-40 kg/m2
- Blood uric acid above 405 μmol/l (6.8 mg/dl)
- Willing to abstain from regular consumption of probiotic supplements or food products containing probiotic bacteria (including fermented food and beverages) during the study
- Willing to abstain from regular consumption of supplements and medications known to alter gastrointestinal function or inflammatory status during the study
Exclusion
- Recent (within last month) episode of gout
- Diagnosis of type 1 diabetes
- Diagnosed inflammatory bowel disease (IBD)
- Current diagnosis of psychiatric disease/s or syndromes
- Current diagnosis of neurodegenerative disease
- Current pregnancy or breastfeeding
- History of complicated gastrointestinal surgery
- (Partial) resection of the small intestine or colon
- Regular use of urate-lowering treatment (apart from allopurinol) in the month prior to inclusion
- Oral or intravenous administration of antibiotics and/or corticosteroids in the 4 months prior to inclusion
- Regular use of any non-steroidal anti-inflammatory drug (NSAID) during the last month prior to inclusion (apart from low-dose acetylsalicylic acid)
- Consumption of more than 9 standard glasses of alcohol-containing drinks per week and/or more than 4 standard glasses per occasion
- Regular use of probiotic or prebiotic supplementation in the month prior to inclusion
- Any condition or intake of medication which could substantially interfere with the outcome of the study, as decided by the principal investigator's discretion
Key Trial Info
Start Date :
September 15 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2027
Estimated Enrollment :
99 Patients enrolled
Trial Details
Trial ID
NCT07141888
Start Date
September 15 2025
End Date
December 1 2027
Last Update
September 12 2025
Active Locations (1)
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1
Örebro University
Örebro, Sweden