Status:
NOT_YET_RECRUITING
Synovial Fluid Withdrawal or PRP Injection For Acute ACL Tears and Cytokines
Lead Sponsor:
Rush University Medical Center
Collaborating Sponsors:
Arthroscopy Association of North America (AANA)
Conditions:
Posttraumatic Osteoarthritis
Anterior Cruciate Ligament (ACL) Rupture
Eligibility:
All Genders
18-50 years
Phase:
NA
Brief Summary
The purpose of this study is to determine what effects the withdrawal of excess knee joint fluid or the injection of a factor from the blood has on swelling after a sudden anterior cruciate ligament (...
Detailed Description
The body responds to different stresses by releasing factors in the blood and fluids in response to stressors like injury, surgery or certain treatments. Some of these factors help heal and some make ...
Eligibility Criteria
Inclusion
- Age 18 - 50
- English-speaking
- Clinical evidence of ACL rupture with swelling
- Participant must be undergoing ACL reconstruction surgery
Exclusion
- Age \<18 or \>50
- Presentation \>3 weeks after initial injury
- Previous traumatic ipsilateral (same side) knee injury consistent with chronic ACL tear or prior ACL surgery
- \> Kellgren-Lawrence grade 2 changes on preoperative x-ray
- History of hemophilia or inflammatory arthropathy (e.g., rheumatoid arthritis)
Key Trial Info
Start Date :
January 1 2026
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2028
Estimated Enrollment :
99 Patients enrolled
Trial Details
Trial ID
NCT07142369
Start Date
January 1 2026
End Date
December 1 2028
Last Update
December 5 2025
Active Locations (1)
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1
Rush University Medical Center
Chicago, Illinois, United States, 60612