Status:
COMPLETED
ED50 of Dexmedetomidine as an Adjuvant to 0.5% Hyperbaric Bupivacaine 12.5 mg for Spinal Anesthesia in Hip and Knee Surgery: An Up-and-Down Method Approach
Lead Sponsor:
Indonesia University
Conditions:
Knee Surgery
Pelvic Surgery
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
Determine ED50 dexmedetomidine adjuvant that can provide spinal anesthetic sensory blockade duration of 200 minutes on knee and pelvis surgery with up-and-down method.
Eligibility Criteria
Inclusion
- 18-60 years old
- Pelvic or knee surgery patient with American Society of Anesthesiologists physical status I - III with epidural spinal anesthesia
- Body mass index 18-35 kg/m2
- Body height 150-180 cm
- Willing to become a research participant
Exclusion
- Have a history of allergy to bupivacaine or dexmedetomidine
- Have sensory or motoric disabilities in the lower extremity contralateral to the surgery area
- Have a history of congestive heart failure and/or heart rhythm disorder
- Have regional anesthesia contraindication
Key Trial Info
Start Date :
February 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 31 2025
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT07144215
Start Date
February 1 2025
End Date
May 31 2025
Last Update
September 5 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
RSUPN Cipto Mangunkusumo
Jakarta Pusat, Jakarta Special Capital Region, Indonesia, 10430