Status:
COMPLETED
Parasternal Intercostal Ultrasound vs RSBI for Weaning Prediction
Lead Sponsor:
Benha University
Conditions:
Respiratory Insufficiency
Weaning, Ventilator
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
Mechanical ventilation is essential in the management of critically ill patients, but deciding the proper time to wean and extubate remains a significant challenge. Extubation failure is associated wi...
Eligibility Criteria
Inclusion
- Age 18 years or older
- Both sexes
- Patients invasively mechanically ventilated for up to 24 hours and ready to undergo a spontaneous breathing trial
- Patients considered ready for spontaneous breathing trial if all of the following were met:
- Alert and afebrile
- Fraction of inspired oxygen less than 50 percent
- Positive end-expiratory pressure less than or equal to 8 centimeters of water
- Ratio of arterial oxygen partial pressure to fraction of inspired oxygen greater than 200
- Arterial blood pH between 7.35 and 7.45
- Respiratory rate less than or equal to 35 breaths per minute
- Hemodynamically stable without vasopressor support
Exclusion
- Age younger than 18 years
- Pregnancy
- Surgical dressings near or over the sternum that prevent ultrasound examination
- Body mass index less than 18.5 kilograms per square meter (underweight)
- Body mass index greater than or equal to 40 kilograms per square meter (morbid obesity)
- Primary neuromuscular diseases
Key Trial Info
Start Date :
October 3 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 25 2024
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT07144878
Start Date
October 3 2023
End Date
June 25 2024
Last Update
August 28 2025
Active Locations (1)
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1
Benha University Hospital
Banhā, Egypt