Status:
NOT_YET_RECRUITING
sperDNA Fragmentation a a Predictor for Outcome After Varicocelectomy,m
Lead Sponsor:
Assiut University
Conditions:
DNA Damage
Eligibility:
MALE
20-45 years
Brief Summary
Varicocele is often associated with infertility and reduction in sperm quality, and it is one of the most common causes of reversible male infertility. The exact mechanism of infertility caused due t...
Detailed Description
Varicocele is often associated with infertility and reduction in sperm quality, and it is one of the most common causes of reversible male infertility. The prevalence of clinically relevant varicocel...
Eligibility Criteria
Inclusion
- Patients have been diagnosed with VC (GII and GIII) by physical examination and scrotal color Doppler ultrasonography.
- Patients with stable relationships.
- In the control group, those with high SDF.
- Patients with documented infertility.
- Normal female partners or having correctable cause of infertility.
- Patients age from 20 to 45 years old.
Exclusion
- Patients with a history of scrotal and spermatic cord injuries and congenital genitourinary abnormalities.
- Patients with systemic or endocrine disease, cryptorchidism, hypogonadism, genital infection, hormonal treatment and azoospermic patients.
- Recurrent varicocele.
- Patients with any other disease that may cause VC (such as external kidney tumor, hydronephrosis, etc.)
- Smoker patients and others risk factors (x ray, nuclear) workers
- Abnormal or uncorrectable female factor. 7- Single patient.
Key Trial Info
Start Date :
October 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 1 2026
Estimated Enrollment :
1 Patients enrolled
Trial Details
Trial ID
NCT07144891
Start Date
October 1 2025
End Date
October 1 2026
Last Update
August 28 2025
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