Status:
RECRUITING
Cognitive-Motor Incorporated Training and Its Relations in Cerebrovascular Diseases With Cognitive and Motor Impairments
Lead Sponsor:
National Taiwan University Hospital
Conditions:
Moyamoya Disease
Healthy
Eligibility:
All Genders
20-100 years
Phase:
NA
Brief Summary
The following three-part proposal will explore the impact of applying motor-cognitive incorporated training (MCIT) in individuals with post-stroke cognitive impairment (PSCI) or Moyamoya disease (MMD)...
Eligibility Criteria
Inclusion
- Part 1:
- For aged-matched healthy controls:
- being 20 years of age or older
- the ability to stand for more than 30 seconds
- a MoCA score of higher than 26.
- For PSCI participants:
- Diagnosis of stroke confirmed by brain CT or MRI, with symptom onset more than 7 days prior (subacute or chronic phase)
- Being 20 years of age or older
- The ability to stand for more than 30 seconds
- a MoCA score of less than 26
- For the MMD group:
- a confirmed diagnosis of Moyamoya disease or Moyamoya syndrome through CT scan or angiography
- If stroke occurred, being in the subacute phase (one week post-stroke)
- being 20 years of age or older
- the ability to stand for more than 30 seconds
- a MoCA score of less than 26
Exclusion
- unstable or uncontrolled vital signs, including a resting heart rate \>100 or \<40 BPM, a respiratory rate \>20 or \<12 breaths per minute, an SpO2 \< 95%, a central arterial pressure (CAP) \<80 mmHg, and individuals requiring ICP monitoring will also be excluded
- requiring invasive mechanical ventilation or being deemed unsuitable by the attending physician due to unstable medical conditions
- the presence of other neurological disorders or unstable vital signs may interfere with the experiment
- currently hospitalized in the intensive care unit (ICU)
- less than 12 years of education
- Severe visual or hearing impairments, or communication and comprehension difficulties that interfere with study participation
- Part 2:
- Inclusion Criteria:
- Diagnosis of stroke confirmed by brain CT or MRI, with symptom onset more than 7 days prior (subacute or chronic phase)
- Being 20 years of age or older
- The ability to stand for more than 30 seconds
- a MoCA score of less than 26
Key Trial Info
Start Date :
March 10 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 31 2028
Estimated Enrollment :
210 Patients enrolled
Trial Details
Trial ID
NCT07144930
Start Date
March 10 2025
End Date
August 31 2028
Last Update
August 28 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
National Taiwan University
Taipei, Taiwan