Status:
NOT_YET_RECRUITING
Cilostazol With Nimodipine to Improve Outcome After Aneurysmal Subarachnoid Hemorrhage
Lead Sponsor:
Centre Hospitalier St Anne
Conditions:
Aneurysmal Subarachnoid Hemorrhage
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
The CASH study is a randomized, double-blind, placebo-controlled trial evaluating whether adding cilostazol to standard nimodipine therapy improves neurological outcomes in patients with aneurysmal su...
Detailed Description
The CASH trial (Cilostazol in Aneurysmal Subarachnoid Hemorrhage) is a multicenter, randomized, double-blind, placebo-controlled Phase III clinical trial investigating whether the addition of cilostaz...
Eligibility Criteria
Inclusion
- Adult patients admitted to an ICU with SAH related to a ruptured cerebral aneurysm occurring within the last 96 hours.
- Aneurysm successfully secured by surgical clipping or endovascular coiling
- Consent of the patient or, if not possible, from a proxy (emergency clause).
- Registration in a national health care system
Exclusion
- \- Precritical modified Rankin Scale (mRS) \> 2
- Nonaneurysmal SAH
- Delayed \>96h admission after first symptoms of SAH
- Coma defined by GCS of 3-5 with untreatable aneurysm will be excluded"
- Known allergy to cilostazol
- Pregnancy
- Pre-existing major hepatic, renal, pulmonary or cardiac disease
- Concomitant use of one other anti-platelet and/or anticoagulant agent
- SAH diagnosed on Lumbar puncture with no evidence of blood on CT.
- Tutelage or guardianship
Key Trial Info
Start Date :
December 15 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 14 2029
Estimated Enrollment :
630 Patients enrolled
Trial Details
Trial ID
NCT07144956
Start Date
December 15 2025
End Date
December 14 2029
Last Update
September 10 2025
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.