Status:

NOT_YET_RECRUITING

Expression Pattern and Possible Clinical Significance of CD81 In Myeloid Leukemia

Lead Sponsor:

Assiut University

Conditions:

Acute Myeloid Leukemia

Chronic Myeloid Leukemia

Eligibility:

All Genders

18+ years

Brief Summary

The goal of this study is to understand how the protein CD81 affects myeloid leukemia (especially AML) and whether it can help predict patient outcomes or guide treatment. The main question it aims t...

Detailed Description

CD81, a cell surface protein belonging to the tetraspanin family, is overexpressed in 60-90% of acute myeloid leukemia (AML) patients and correlates with aggressive disease manifestations. Clinically,...

Eligibility Criteria

Inclusion

  • 1\. Myeloid leukemia patients 2. Patients of both genders (Males and females) at any age 3. Cases are de novo (Not on treatment)

Exclusion

  • . Patients with other haematological neoplasms (ALL,CLL, plasma cell myeloma, etc)
  • Patients under any therapeutic intervention
  • Patients with current or previous other malignancies at time of diagnosis

Key Trial Info

Start Date :

October 1 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

March 1 2028

Estimated Enrollment :

66 Patients enrolled

Trial Details

Trial ID

NCT07146542

Start Date

October 1 2025

End Date

March 1 2028

Last Update

August 28 2025

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