Status:

RECRUITING

Symptoms of Immune Checkpoint Inhibitor Therapy in Cutaneous Melanoma

Lead Sponsor:

University of California, San Francisco

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Cutaneous Melanoma

Cutaneous Melanoma, Stage III

Eligibility:

All Genders

18+ years

Brief Summary

The introduction of immune checkpoint inhibitors (ICIs) for the treatment of patients with stages IIB to IV cutaneous melanoma resulted in dramatic improvements in mortality rates for this common form...

Detailed Description

PRIMARY OBJECTIVES: 1. Evaluate for changes over time in the patients' symptom experience, 2. Identify distinct symptom profiles over time. 3. Evaluate for demographic, clinical, environmental, and m...

Eligibility Criteria

Inclusion

  • Adults ≥18 years of age
  • Able to speak and read English
  • Diagnosed with stage IIB, III, or IV cutaneous melanoma
  • Participants who are scheduled to receive \>=1 immune checkpoint inhibitor at University of California San Francisco medical center locations. Participants on targeted therapies (e.g., BRAF or mitogen-activated extracellular signal-regulated kinase (MEK) inhibitors) will be eligible.
  • Provide written informed consent to participate in this study.
  • Participants with stage IIB or higher cutaneous melanoma

Exclusion

  • Participants will be excluded if they are unable to complete study requirements.

Key Trial Info

Start Date :

October 13 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 30 2027

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT07148245

Start Date

October 13 2025

End Date

June 30 2027

Last Update

November 7 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

University of California, San Francisco

San Francisco, California, United States, 94143