Status:
NOT_YET_RECRUITING
Changes of Ciprofol Dosage and Bispectral Index Required for Loss of Consciousness in Patients of Different Ages
Lead Sponsor:
General Hospital of Ningxia Medical University
Conditions:
Ciprofol
Eligibility:
All Genders
3+ years
Brief Summary
This study aims to explore dose requirements for loss of consciousness and bispectral index changes during general anesthesia induction with ciprofol in patients of different ages, providing a referen...
Detailed Description
Ciprofol, a novel gamma-aminobutyric acid (GABA) receptor agonist, is structurally modified from propofol by adding a cyclopropyl group to its side chain, forming an R-type chiral structure. This modi...
Eligibility Criteria
Inclusion
- 1\) The ASA classification I-II 2) BMI range: 18.5 \< BMI ≤ 24.9 kg/m² 3) Scheduled for elective general anesthesia surgery 4) Signed informed consent by the patient or legal guardian
Exclusion
- 1\) Patients with central nervous system disorders or using medications affecting the central nervous system 2) Patients with cardiac, hepatic, pulmonary, or renal dysfunction 3) History of alcohol or drug abuse 4) Allergy to the study drug 5) Patients with hematologic or metabolic diseases 6) Participation in other drug clinical trials within the past 4 weeks 7) Refusal to participate in the study
Key Trial Info
Start Date :
September 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 20 2025
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT07148596
Start Date
September 1 2025
End Date
December 20 2025
Last Update
August 29 2025
Active Locations (1)
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1
General Hospital of Ningxia Medical University
Yinchuan, Ningxia, China