Status:
RECRUITING
Perception of Pain During Gender Affirming Hormone Therapy
Lead Sponsor:
Medical University of Vienna
Conditions:
Transgender Persons
Pain Threshold
Eligibility:
All Genders
18+ years
Brief Summary
It is known from the literature that women and men differ in their perception of pain. Why this is the case has not been conclusively clarified. Sex hormones could have a significant influence on this...
Eligibility Criteria
Inclusion
- ≥ 18 years of age
- Assigned female at birth (AFAB)
- Diagnosed gender identity disorder/gender dysphoria and planned therapy with testosterone OR
- ≥ 18 years of age
- Assigned male at birth (AMAB)
- Diagnosed gender identity disorder/ gender dysphoria and planned therapy with estradiol
Exclusion
- Any sex hormone intake during the last 6 months
- Acute or chronic pain
- Polyneuropathy
- Diagnosis of alcohol or drug addiction
- BMI under 18 or over 35
- Pregnancy
- Breastfeeding
- Pharmacological analgesic therapy within the previous 7 days before each examination
- History of significant trauma or surgery to the hands with residual neurological deficit or pain.
Key Trial Info
Start Date :
December 1 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 1 2026
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT07148921
Start Date
December 1 2024
End Date
March 1 2026
Last Update
August 29 2025
Active Locations (1)
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1
Mecial University of Vienna
Vienna, Vienna, Austria, 1090