Status:
COMPLETED
Probiotic Nanofiber Floss and Subgingival Pathogen Suppression
Lead Sponsor:
St. Anne's University Hospital Brno, Czech Republic
Collaborating Sponsors:
Czech Technology Agency
Ministry of Health, Czech Republic
Conditions:
Dental Hygiene
Probiotics, Periodontitis
Eligibility:
MALE
18+ years
Phase:
NA
Brief Summary
This randomized, double-blind, crossover clinical trial evaluated the effect of a probiotic-containing nanofiber dental floss on subgingival red complex periopathogens and gingival health in periodont...
Detailed Description
The study aimed to validate a targeted subgingival delivery method using Ligilactobacillus salivarius-infused nanofiber floss. Participants received both floss types in a crossover design. Clinical pa...
Eligibility Criteria
Inclusion
- Male adults (≥18 years) of Czech or Slovak nationality
- ≥20 own teeth
- Good oral hygiene
- Maximum Stage 2 periodontitis
Exclusion
- Immunocompromised status
- Systemic illness
- Antibiotic use within 2 months
- Smoking
- Probiotic use during study
Key Trial Info
Start Date :
February 1 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 24 2022
Estimated Enrollment :
33 Patients enrolled
Trial Details
Trial ID
NCT07149493
Start Date
February 1 2022
End Date
June 24 2022
Last Update
September 2 2025
Active Locations (1)
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1
St. Anne's University Hospital
Brno, Czechia, 65691