Status:

RECRUITING

The Effects of Platelet Rich Plasma Adjuvant to Type I/III Collagen Ratio, Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 in Pelvic Organ Prolapse Repair

Lead Sponsor:

Andalas University

Collaborating Sponsors:

Faculty of Medicine, Andalas University

Dr. M Djamil Hospital, Padang

Conditions:

Pelvic Organ Prolapse Vaginal Surgery

Platelet Rich Plasma Injection

Eligibility:

FEMALE

45-65 years

Phase:

NA

Brief Summary

The goal of this clinical trial is to analyze the effect of Platelet Rich Plasma (PRP) Adjuvant To Type I/III Colagen Ratio, MMP-2 and MMP-9 in Pelvic Organ Prolapse Repair. The main questions it aim...

Detailed Description

1. Prepare tools and materials for the research. 2. Align perceptions with the research team to conduct well-guided interviews. 3. Patients who meet the inclusion and exclusion criteria will be given ...

Eligibility Criteria

Inclusion

  • Patients with second-degree or higher pelvic organ prolapse
  • Postmenopausal pelvic organ prolapse patients
  • Patients with pelvic organ prolapse who will undergo surgery
  • Willingness to participate in the study

Exclusion

  • Patients with gynecological malignancies
  • Patients with a history of collagen disease
  • Patients with blood disorders

Key Trial Info

Start Date :

August 27 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 1 2026

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT07150442

Start Date

August 27 2025

End Date

August 1 2026

Last Update

September 8 2025

Active Locations (1)

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Biomedical Science Doctoral Programme Faculty of Medicine Andalas University/ Urogynecology Division Obstetrics and Gynecology Department M Djamil Hospital Padang

Padang, West Sumatera, Indonesia

The Effects of Platelet Rich Plasma Adjuvant to Type I/III Collagen Ratio, Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 in Pelvic Organ Prolapse Repair | DecenTrialz