Status:

COMPLETED

A Study of Real-world Treatment and Burden of Chronic Myeloid Leukemia Patients in Japan

Lead Sponsor:

Novartis Pharmaceuticals

Conditions:

Myeloid Leukemia, Chronic

Eligibility:

All Genders

15+ years

Brief Summary

The main goal of this study was to describe treatment patterns of patients with chronic myeloid leukemia (CML) who were treated with tyrosine kinase inhibitors (TKIs) in Japan. This was a retrospecti...

Eligibility Criteria

Inclusion

  • Patients who met all the below inclusion criteria and none of the exclusion criteria were included in the study.
  • Inclusion criteria:
  • Patients who had at least one TKI prescription during the selection period,
  • a confirmed diagnosis of chronic phase CML recorded before or at the index date,
  • were aged 15 years or older at the index date, and
  • had at least 12-months continuous pre-index period.
  • Exclusion criteria:
  • Patients who had at least one TKI prescription in the 12 months preceding the index date (washout period to catch the 1st line of treatment \[LoT\]),
  • a confirmed diagnosis of CML blast crisis or accelerated phase recorded prior to, at, or within 6 months after the index date,
  • a confirmed diagnosis of acute myeloid leukemia (AML) or acute lymphoblastic leukemia (ALL) within 6 months after the index date,
  • a medical record of chemotherapy (not including hydroxyurea) within 6 months after the index date,
  • a stem cell transplant procedure recorded during the pre-index period.

Exclusion

    Key Trial Info

    Start Date :

    July 5 2022

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    February 8 2023

    Estimated Enrollment :

    754 Patients enrolled

    Trial Details

    Trial ID

    NCT07150793

    Start Date

    July 5 2022

    End Date

    February 8 2023

    Last Update

    September 2 2025

    Active Locations (1)

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    Novartis

    East Hanover, New Jersey, United States, 07936