Status:

COMPLETED

Successful Treatment of Netherton Syndrome With Combination of Secukinumab and Dupilumab

Lead Sponsor:

Federal Research Institute of Pediatric Hematology, Oncology and Immunology

Conditions:

Neterton Syndrome

Eligibility:

All Genders

Up to 18 years

Brief Summary

In this study, we describe our experience with secukinumab (IL-17A inhibitor) and dupilumab (IL-4/IL-13 inhibitor) treatment of a group of pediatric patients with severe Neterton syndrome.

Detailed Description

Pediatric patients qualified for participation in the study if they had a documented diagnosis of Neterton syndrome and they received treatment with sekukinumab or dupilumab for at least 3 months. Al...

Eligibility Criteria

Inclusion

  • Pediatric patients with Neterton syndrome
  • Treatment with secukinumab and/or dupilumab for at least 3 months

Exclusion

  • Irregular administration of therapy
  • Development of a serious adverse event

Key Trial Info

Start Date :

December 19 2023

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 10 2025

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT07151508

Start Date

December 19 2023

End Date

January 10 2025

Last Update

September 5 2025

Active Locations (1)

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Dmitry Rogachev National Medical Research Center Of Pediatric Hematology, Oncology and Immunology

Moscow, Russia

Successful Treatment of Netherton Syndrome With Combination of Secukinumab and Dupilumab | DecenTrialz