Status:
RECRUITING
(68)Ga-FAPI PET/CT in Patients With ANCA-associated Vasculitis
Lead Sponsor:
Ruijin Hospital
Conditions:
ANCA-associated Vasculitis
Eligibility:
All Genders
18+ years
Brief Summary
Pulmonary and renal involvement are the most common clinical manifestations of antineutrophil cytoplasmic antibody(ANCA)-associated vasculitis (AAV). Studies have shown that both interstitial lung dis...
Eligibility Criteria
Inclusion
- Age over 18 years;
- Meeting the 2022 American College of Rheumatology/European Alliance of Associations for Rheumatology (ACR/EULAR) classification criteria for ANCA-associated vasculitis;
- Diagnosed with concomitant interstitial lung disease based on High-Resolution Computed Tomography (HRCT) images obtained within one year prior to enrollment, interpreted by two radiologists blinded to clinical information;
- Complete clinical information available;
- Signed and dated informed consent form;
- Willingness to comply with the study procedures and cooperate throughout the entire study process.
Exclusion
- Presence of other rheumatic diseases;
- Presence of other conditions that may cause interstitial lung disease or renal impairment, such as systemic lupus erythematosus, dermatomyositis, or rheumatoid arthritis;
- History of, or planned, hematopoietic stem cell transplantation;
- Presence of severe comorbidities deemed by the investigators to be unsuitable for participation in this clinical study, such as severe cardiopulmonary insufficiency, severe bone marrow suppression, or severe hepatic or renal insufficiency;
- Acute abdominal emergencies such as intestinal perforation or complete intestinal obstruction;
- Pregnant or potentially pregnant women, and lactating women;
- Poor treatment compliance.
Key Trial Info
Start Date :
September 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 1 2028
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT07151521
Start Date
September 1 2025
End Date
July 1 2028
Last Update
November 17 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Ruiiin Hospital Shanghai JiaoTong University School of Medicine
Shanghai, China, 200025