Status:
RECRUITING
Effects of Resistance Exercises in Hereditary Sensory-Motor Neuropathy (Charcot-Marie-Tooth Disease)
Lead Sponsor:
Universidad de La Frontera
Conditions:
Polyneuropathy
Charcot Marie Tooth Disease (CMT)
Eligibility:
All Genders
15-29 years
Phase:
NA
Brief Summary
The goal of this clinical trial is to compare the effects of an 8-week resistance exercise training program on skeletal muscle quality, functional capacity, and quality of life in young individuals ag...
Detailed Description
Introduction: Hereditary sensorimotor polyneuropathy (HSPN), also known as Charcot-Marie-Tooth disease (CMT), is the most prevalent group of hereditary neuromuscular disorders. It is characterized by ...
Eligibility Criteria
Inclusion
- Men or women between 15 and 29 years of age with a diagnosis of hereditary sensorimotor polyneuropathy (HSPN) in any of its subtypes, living in the community (for experimental group).
- Healthy men or women between 15 and 29 years of age living in the community (for control group).
- Having active ankle movement within a range from plantarflexion to at least 0° of ankle dorsiflexion, allowing for strength training.
Exclusion
- Osteoarticular or mobility impairments that prevent safe performance of resistance exercise training (e.g., ankle arthrodesis).
- Use of nutritional supplements that may affect skeletal muscle regulation (leucine, glutamine, casein, whey protein, fatty acids, creatine, among others).
- Untreated and/or uncontrolled chronic diseases or intellectual disability.
- History of surgery
- Participation in a resistance exercise training program within the past 6 months.
Key Trial Info
Start Date :
September 20 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 20 2026
Estimated Enrollment :
22 Patients enrolled
Trial Details
Trial ID
NCT07152197
Start Date
September 20 2025
End Date
September 20 2026
Last Update
September 23 2025
Active Locations (2)
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1
Temuco, Chile
Temuco, La Araucanía, Chile, 4812790
2
Universidad de La Frontera
Temuco, La Araucanía, Chile, 4812790