Status:

RECRUITING

Assessing Bone Fracture Healing Effect of Almonds

Lead Sponsor:

Aga Khan University Hospital, Pakistan

Collaborating Sponsors:

University of Karachi

PharmEvo Pvt Ltd

Conditions:

Femur Shaft Fracture

Tibia Fractures

Eligibility:

All Genders

18-55 years

Phase:

NA

Brief Summary

Femur and tibia shaft fractures are common after trauma with a burden of 5% and 20% respectively. Clinicians recommend costly bone strengthening drugs/supplements while treating bone fractures. These ...

Detailed Description

Trauma is a leading cause of morbidity and mortality in low middle income countries with road traffic accident as a common mechanism of trauma. Femur and tibia shaft fractures are common with a burden...

Eligibility Criteria

Inclusion Criteria:

  1. Patients of 18 to 55 years of age of any gender.
  2. Agree and able to voluntary participate.
  3. Patients with trauma associated femur fracture and tibia shaft fracture arriving at hospital for treatment.

Exclusion Criteria:

  1. Mentally retarded or patients with severe psychiatric illness.
  2. Patients are already on bone-strengthening drugs (bisphosphonates, vitamin D, strontium ranelate, teriparatide, etc.).
  3. Patients who require bone-strengthening drugs for osteoporosis or for any urgent need.
  4. Severe cardiovascular, hepatic, or renal disease.
  5. Known allergy or toxicity to Prunus dulcis (almonds) and/or vitamin D supplements.

Key Trial Info

Start Date :

August 20 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 1 2026

Estimated Enrollment :

136 Patients enrolled

Trial Details

Trial ID

NCT07153302

Start Date

August 20 2024

End Date

July 1 2026

Last Update

September 3 2025

Active Locations (1)

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The Aga Khan University

Karachi, Pakistan, 74800