Status:

ENROLLING_BY_INVITATION

Effect of Cross-Education in Blood Flow Restriction Resistance Training on Lower Limbs in Older Women

Lead Sponsor:

Paulista University

Conditions:

Muscle Strength

Hypertrophy

Eligibility:

FEMALE

60+ years

Phase:

NA

Brief Summary

Unilateral resistance training has been shown to promote strength adaptations in the directly trained limb and also improve strength in the contralateral limb, a phenomenon known as cross-education (C...

Detailed Description

A randomized controlled clinical trial will be conducted with 32 older women aged 60 years or older. Participants will be randomly assigned to one of two groups: a low-intensity unilateral resistance ...

Eligibility Criteria

Inclusion

  • Elderly women who present one or more of the following characteristics will not be included:
  • a history of stroke, progressive neurological disease, or dementia;
  • communication difficulties due to aphasia or hearing loss;
  • any health condition that contraindicates or prevents physical exercise;
  • a history of hip or knee surgery (e.g., arthroscopy or arthroplasty) or recent lower limb musculoskeletal injury that could impair performance during tests or training (e.g., osteoarthritis, osteoporotic fracture, muscle injury, and/or back pain in the past six months);
  • use of supplements aimed at improving physical performance and/or muscle mass; or
  • one or more predisposing risk factors for thromboembolism.

Exclusion

  • Participants will be excluded from the study if they use medications (analgesics or anti-inflammatory drugs) or other therapeutic interventions that could interfere with any outcomes, or if they sustain an injury resulting from the training and choose to withdraw from the study.

Key Trial Info

Start Date :

August 11 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2025

Estimated Enrollment :

32 Patients enrolled

Trial Details

Trial ID

NCT07155967

Start Date

August 11 2025

End Date

December 1 2025

Last Update

September 12 2025

Active Locations (1)

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1

Franciele Marques Vanderlei

Presidente Prudente, São Paulo, Brazil, 19060-900