Status:
RECRUITING
Pathogenic Insights and Search for Biomarkers in RFC1-ataxia/CANVAS
Lead Sponsor:
Catholic University of the Sacred Heart
Conditions:
CANVAS Syndrome
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
CANVAS (Cerebellar Ataxia, Neuropathy, Vestibular Areflexia Syndrome), also referred to as RFC1-ataxia, is a recently molecularly characterized neurodegenerative disorder caused by a biallelic expansi...
Detailed Description
The research proposal recognizes as the primary aim to evaluate and compare the sensitivity of individual validated clinical rating scales in assessing global disease severity and/or progression in a ...
Eligibility Criteria
Inclusion
- Molecular diagnosis of RFC1-ataxia
- age \>18 years and \<80 years
- ability to sign informed consent
Exclusion
- Diagnosis of other degenerative and/or non-degenerative neurological diseases
- Not signed informed consent
Key Trial Info
Start Date :
October 14 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 31 2026
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT07156214
Start Date
October 14 2024
End Date
July 31 2026
Last Update
September 5 2025
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
Alma Mater Studiorum University of Bologna
Bologna, Italy, 40126
2
Department of Neuroscience
Roma, Italy, 00168