Status:

COMPLETED

Prenatal Hormonal Markers and Sleep Characteristics in Young Adults With Joint Hypermobility

Lead Sponsor:

Nigde Omer Halisdemir University

Conditions:

Joint Hypermobility

Healty Controls

Eligibility:

All Genders

18-35 years

Brief Summary

Joint hypermobility is a clinical condition characterized by joints having a range of motion beyond their normal limits. Hormonal factors are thought to play a role in the development of joint hypermo...

Detailed Description

Estrogen affects collagen metabolism and connective tissue structure, which can lead to increased ligament laxity at high levels. Increased estrogen and progesterone during pregnancy cause significant...

Eligibility Criteria

Inclusion

  • Individuals aged 18-35
  • Individuals who scored 5 out of 9 or higher on the Beighton score
  • Control group: Those with a Beighton score of ≤ 4

Exclusion

  • Individuals with any pathology related to the musculoskeletal system
  • Individuals diagnosed with metabolic, neurological, or genetic diseases (tissue diseases such as Ehlers-Danlos syndrome and Marfan syndrome)
  • Those with a history of surgery within the last 6 months
  • Those who are pregnant or breastfeeding

Key Trial Info

Start Date :

August 20 2025

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 17 2025

Estimated Enrollment :

180 Patients enrolled

Trial Details

Trial ID

NCT07157930

Start Date

August 20 2025

End Date

December 17 2025

Last Update

December 24 2025

Active Locations (1)

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Nigde Omer Halisdemir University

Niğde, Turkey (Türkiye)