Status:
RECRUITING
Genicular Nerve Block for Knee Pain in the ED
Lead Sponsor:
University of Pennsylvania
Conditions:
Knee Pain
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Patient with atraumatic knee pain without a large knee effusion on x-ray will be randomized to receive either a genicular nerve block (GNB) or standard of care in the emergency department.
Eligibility Criteria
Inclusion
- Atraumatic knee pain
- \>17 years age
- X-ray of the knee obtained in the ED
- Initial pain score (numeric rating scale) 5-10
Exclusion
- Fracture or dislocation on x-ray
- large knee joint effusion identified on x-ray
- allergy or contraindication to local anesthetics
- History of local anesthetic systemic toxicity after receiving local anesthetics
- Pregnancy
- Incarcerated
- History of knee replacement of affected knee
- Concern for septic joint
- Overlying cellulitis
- Hemodynamic instability
- Altered mental status or inability to consent for procedure.
Key Trial Info
Start Date :
July 16 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 1 2026
Estimated Enrollment :
34 Patients enrolled
Trial Details
Trial ID
NCT07158736
Start Date
July 16 2025
End Date
September 1 2026
Last Update
September 8 2025
Active Locations (4)
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1
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104
2
Pennsylvania Hospital
Philadelphia, Pennsylvania, United States, 19104
3
Pennsylvania Presbyterian Medical Center
Philadelphia, Pennsylvania, United States, 19104
4
HUP Cedar
Philadelphia, Pennsylvania, United States, 19143