Status:

AVAILABLE

Vatiquinone Expanded Access Protocol

Lead Sponsor:

Medical University of South Carolina

Collaborating Sponsors:

PTC Therapeutics

Conditions:

Mitochondrial Disease

Eligibility:

All Genders

1+ years

Brief Summary

The purpose of this study is to provide participants who successfully completed the study titled "An Open-label, Safety Study for Previously Treated Vatiquinone (PTC743) Subjects With Inherited Mitoch...

Detailed Description

This expanded access protocol serves to make Vatiquinone accessible to subjects with inherited mitochondrial disease who previously participated in a Vatiquinone clinical trial at the Medical Universi...

Eligibility Criteria

Inclusion

  • Subjects with molecular genetic mitochondrial disease including Leigh syndrome, and Alpers syndrome.
  • Completed participation in the study titled "An Open-label, Safety Study for Previously Treated Vatiquinone (PTC743) Subjects With Inherited Mitochondrial Disease"
  • In the opinion of the clinical investigator, the continuation to receive Vatiquinone will be of benefit to the participants.
  • Enrollment into a clinical trial to receive Vatiquinone is not possible

Exclusion

  • Current participation in any other interventional study
  • Pregnant or currently breast feeding.

Key Trial Info

Start Date :

Trial Type :

EXPANDED_ACCESS

End Date :

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT07159139

Last Update

September 8 2025

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