Status:

NOT_YET_RECRUITING

Effectiveness of an Interprofessional Approach to the Treatment of Spasticity With Botulinum Toxin & Non-pharmacological Therapies

Lead Sponsor:

Technical University of Bern

Conditions:

Spasticity

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Many people with neurological conditions will experience spasticity, a nonvolitional and uncontrollable tightening and/or spasm of muscles. This can impact the person's functioning and independence in...

Detailed Description

Cross-national, multicenter (CH and UK) single case experimental design (SCED), specifically N-of-1 series with an ABC Design (Baseline, Intervention, Follow-up). Patients with focal or multifocal spa...

Eligibility Criteria

Inclusion

  • Age 18 or over
  • male, female or other
  • acute or chronic spasticity
  • patients who have been assessed by the spasticity MDT and whose treatment plan includes Botulinum toxin and non-pharmacological therapies for focal or multi-focal spasticity and who have signed the general consent at entry.

Exclusion

  • \<18 years
  • Patients with spasticity, who will not receive BoNT
  • Planned re-injection of BoNT before the end of the Phase C Follow-Up
  • Previous BoNT injection within 3 months of baseline measurements

Key Trial Info

Start Date :

October 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 1 2027

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT07160699

Start Date

October 1 2025

End Date

April 1 2027

Last Update

September 8 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

REHAB Basel

Basel, Switzerland, 4055

2

Royal Hospital for Neuro-disability

London, West Hill Putney, United Kingdom, SW15 3 SW