Status:

NOT_YET_RECRUITING

Safety and Performance of the Semical Adhesion Barrier Gel for Prevention of Intra-uterine Adhesion

Lead Sponsor:

Semikal Technology

Collaborating Sponsors:

Antalya Training and Research Hospital

Conditions:

Intrauterine Abnormalities in Infertility

Asherman Syndrome

Eligibility:

FEMALE

18+ years

Brief Summary

The aim of this study was to obtain short- and long-term performance and safety data of cross-linked hyaluronic acid-based adhesion barrier gel used to prevent intrauterine adhesion formation.

Detailed Description

This study was designed as a non-interventional (observational), comparative, retrospective and single-center study. The investigational device has the CE mark under 93/42/ EEC Medical Device Directiv...

Eligibility Criteria

Inclusion

  • Female patients aged 18 and over
  • Patients who were treated with operative hysteroscopy for intrauterine pathology (endometrial polips, myomas with uterine cavity deformation, uterine septa, intrauterine adhesion, ovarian cyst, endometrial cyst, etc.)
  • Patients who had undergone operative hysteroscopy at least 30 days and at most 6 months ago
  • Patients who had second-look office hysteroscopy at least once after an operative hysteroscopy

Exclusion

  • Children and adolescents under 18 years of age
  • Having a body weight of more than 100 kg
  • Surgeries complicated by excessive bleeding; estimated blood loss of more than 100 cc
  • Surgeries complicated with uterine perforation
  • Presence of uncontrolled diabetes, coagulation disorders, and other severe chronic disorders
  • Presence of malignant tumor or diagnosis of cancer, presence of uterovaginal prolapse
  • Concomitant peritoneal grafting or tubal implantation
  • Concomitant intrauterine device implantation
  • Patients without second-look hysteroscopy
  • According to the GDPR and clinical investigation legislation, written informed consent is not mandatory in retrospective studies as long as the patient's personal information is censored.

Key Trial Info

Start Date :

November 1 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2025

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT07160764

Start Date

November 1 2025

End Date

December 31 2025

Last Update

September 8 2025

Active Locations (1)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 1 (1 locations)

1

Antalya Training and Research Hospital Gynecology and Obstetrics Clinic

Antalya, Turkey (Türkiye), 07100