Status:
NOT_YET_RECRUITING
Changes in Body Composition of Patients With Obesity Related Tumors and Their Impact on Clinical Outcomes: a Multicenter Prospective Cohort Study
Lead Sponsor:
Peking Union Medical College Hospital
Conditions:
Obesity Rekated Cancer
Body Composition Changes
Eligibility:
All Genders
18+ years
Brief Summary
Over the past 20 years, China's obesity rates have surged, increasing cancer burden. Obesity links to 13 cancers via metabolic effects of visceral fat and insulin resistance, while sarcopenic obesity ...
Eligibility Criteria
Inclusion
- Age ≥18 years, regardless of gender.
- Histologically or cytologically confirmed obesity-associated malignant tumors (e.g., breast cancer, colorectal cancer, gastric cancer, lung cancer, or thyroid cancer) with planned treatment after diagnosis (any treatment modality permitted).
- No prior chemotherapy, radiotherapy, biologic therapy, immunotherapy, or other antitumor treatments for malignancy.
Exclusion
- Patients with concurrent non-obesity-related malignancies.
- History of prior malignancy (except completely cured carcinoma in situ of the cervix, basal cell carcinoma, or squamous cell carcinoma of the skin).
- Patients with concurrent multiorgan dysfunction syndrome, autoimmune diseases, infectious diseases, neurological disorders, or psychiatric disorders.
Key Trial Info
Start Date :
September 15 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 30 2030
Estimated Enrollment :
6743 Patients enrolled
Trial Details
Trial ID
NCT07161167
Start Date
September 15 2025
End Date
September 30 2030
Last Update
September 8 2025
Active Locations (1)
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1
Peking union medical college hospital
Beijing, Beijing Municipality, China, 100730